How do Mark 16:17–18 signs fit science?
How do the miraculous signs in Mark 16:17–18 (like snake handling and drinking poison) stand up to modern scientific understanding?

Overview of Mark 16:17–18

Mark 16:17–18 reads: “And these signs will accompany those who believe: In My name they will drive out demons; they will speak in new tongues; they will pick up snakes with their hands; and if they drink any deadly poison, it will not harm them; they will lay their hands on the sick, and they will be made well.” These words have often inspired questions about their application to everyday life and how they might fit alongside modern scientific perspectives.

Below is a comprehensive exploration of this topic, unfolding both the biblical context and the broader outlook that incorporates manuscript evidence, historical incidents, and philosophical considerations.


1. Context and Purpose of the Passage

This passage appears at the end of Mark’s Gospel, where Jesus commissions His followers to preach the gospel. The signs listed—casting out demons, speaking in tongues, handling snakes, drinking poisons, and healing the sick—are presented as supernatural endorsements of the message being proclaimed.

In the broader cultural context of the first century, miraculous signs were understood as confirmations of divine authority. Much as Old Testament prophets performed mighty works as evidence of God’s presence (e.g., Elijah on Mount Carmel in 1 Kings 18), the early believers also experienced supernatural signs testifying to the truth of their gospel (Acts 14:3).


2. Reliability of the Text and Manuscript Evidence

Scholars and textual critics, examining ancient Greek manuscripts such as Codex Sinaiticus and Codex Vaticanus, have noted that Mark 16:9–20 is absent from a few early manuscripts. However, the overwhelming majority of later Greek manuscripts contain this passage. Early church writings, such as the Diatessaron (2nd century) and testimonies by church fathers (e.g., Irenaeus in the late 2nd century), reference these verses. These witnesses point to a strong historical footprint for Mark 16:9–20.

From a faith perspective, the Church has traditionally embraced these verses as consistent with the rest of Scripture’s miraculous themes. This passage is also in harmony with other biblical occurrences (Luke 10:19; Acts 28:3–6), underlining God’s protection for His people when carrying out His mission.


3. Interpreting Snake Handling and Poison

The specific signs—picking up snakes and drinking poison—should be viewed in light of the biblical narrative rather than as an everyday command for believers. For instance, Acts 28:3–6 recounts an incident where Paul was bitten by a viper and suffered no ill effects. This event reveals the principle of divine protection, not a license to intentionally seek out danger.

1) Biblical Accounts of Protection: Old Testament examples, such as Daniel’s miraculous preservation in the lions’ den (Daniel 6), mirror this idea. God can suspend natural harm as He wills, demonstrating His supremacy over creation.

2) Not a Mandate for Recklessness: Jesus Himself refused to test God by throwing Himself from the pinnacle of the temple (Matthew 4:5–7). Hence, believers are counseled not to deliberately expose themselves to harm to “prove” their faith.

3) Faith Over Fear: The passage conveys a message of confidence in God’s safeguarding hand during the proclamation of the gospel, not a guarantee of personal invincibility.


4. Scientific Understanding of Snake Venom and Poison

Snake venom and poisonous substances are well-studied terrains in modern science. Toxicology indicates that many venoms can lead to severe injury or death if not treated promptly. Nevertheless, anecdotal reports and documented cases exist in which individuals have survived unusually dangerous exposures, often attributed to timely medical intervention or inexplicable recoveries.

In certain regions, such as rural Appalachia in the United States, groups have taken the reference to snake handling as a literal practice of faith. While these practices have sparked debate and medical concern, they underscore the belief in divine intervention that Mark 16:17–18 affirms. Researchers and journalists covering these communities often encounter testimonies of individuals who claim protection through prayer and faith.

It is vital to note that genuine faith does not typically dismiss the validity of medical knowledge. Rather, many see medical advances as part of divine blessing and are grateful for antidotes and treatments while also recognizing that miracles can occur.


5. Connection with Other Miraculous Signs

Miraculous preservation from venom or poison is only one category of signs in Mark 16. Other listed signs—casting out demons, speaking in new tongues, and healing the sick—can be studied with modern science in mind. Throughout history, believers have recorded numerous instances of physical healings and deliverances that defy medical explanation. Studies in fields like psychiatry and psychosomatic medicine occasionally document recoveries that cannot be fully accounted for by known scientific mechanisms.

Such events reinforce the biblical assertion that while science observes and describes natural processes, the Source of all life can operate in ways beyond our conventional understanding. Scientific inquiry, in its scope and method, does not negate the possibility of the miraculous; it merely cannot definitively measure divine action.


6. Theological Considerations and Practical Application

This passage does not instruct believers to court danger; rather, it serves as an assurance of God’s power and protection in unforeseen, perilous situations. The overarching biblical appeal is to trust in God’s omnipotence, knowing that He may choose to demonstrate His power in extraordinary ways:

Faith and Protection: Believers through the ages have found confidence in the promise that God can preserve those He calls to fulfill His purposes.

Spiritual Discernment: Many theologians interpret the “snake handling” and “drinking poison” references as descriptive of miraculous signs that would follow the early proclamation of the gospel, rather than a prescriptive practice for all time.

Sovereignty of God: Scripture underscores that miraculous events, including protection from harm, are subject to God’s will and timing (Hebrews 2:4).


7. Summary and Encouragement

When held up to modern scientific understanding, the miraculous signs in Mark 16:17–18 function as testimonies to divine power rather than violations of nature for mere spectacle. While toxicology and medical science indeed show how lethal snake venom and poison can be, these verses remind readers that God’s intervention transcends natural limitations in particular circumstances, as evidenced by events recorded in the biblical narrative and contemporary testimonies of remarkable recoveries and protection.

The core message of these verses centers on God’s active participation in human affairs and His ability to protect and direct those He calls. Rather than a directive to experiment with danger, Mark 16:17–18 affirms the limitless power and loving care of the One who commands believers to “go into all the world and preach the gospel” (Mark 16:15).

Why omit Mark 16:9–20 in some texts?
Top of Page
Top of Page