1. What does the phrase "rend the heavens and come down" signify about the people's desire for God's intervention?

2. How does Isaiah depict the consequences of sin in this chapter?

3. How is God's unmatched power portrayed in the first few verses?

4. How does Isaiah’s depiction of Israel's state of desolation relate to our own experiences of spiritual desolation?

5. What does the comparison of righteous deeds to "filthy rags" tell you about our own righteousness apart from God?

6. Why do you think Isaiah calls the people of Israel "the work of Your hands" in his plea to God?

7. How does Isaiah balance acknowledging the people's sin with asking for God's mercy?

8. How does Isaiah 64 challenge our perception of God's judgment and mercy?

9. How can we apply the lessons from Isaiah 64 in our own prayers and supplications?

10. How does the imagery of a destroyed and abandoned Jerusalem relate to the state of our world today?

11. In what areas of your life do you long for God's divine intervention?

12. If you were in Isaiah's situation, how would you approach God in prayer?

13. How can we cultivate a heart that acknowledges personal sin and the need for repentance?

14. What are the implications for us today of God’s wrath, as portrayed in this chapter?

15. How does the concept of God being our Father, as Isaiah appeals, comfort or challenge you in your current circumstances?

16. How does Isaiah's plea to God not to remember their sins forever resonate with your understanding of God's grace and forgiveness?

17. In what ways can we seek God's intervention in the desolation we see in our world today?

18. How can this chapter inspire a reevaluation of our own behaviors and actions?

19. How can the yearning expressed in Isaiah 64 inform our personal relationship with God?

20. How does Isaiah's dialogue with God in this chapter inform your views on prayer, confession, and supplication?