1. The Liberia Mission was commenced in 1833, by the Rev. M. B. Cox, who, in a few short months after, was called to his eternal reward. His dying language was, "Though a thousand fall, Africa must not be given up." Five other missionaries have fallen in the same field. The Liberia mission now includes an annual conference of seventeen preachers, all colored, except the superintendent and the two brethren recently sent out. It has a membership of nearly one thousand, of whom one hundred and fifty are natives. There are thirteen day schools, in which from five hundred to six hundred children are instructed, (of whom about forty are natives, preparing for future usefulness,) fourteen churches, eight mission-houses, three school-houses, one academy, (a stone building,) and one printing-office. Total of missionaries, male and female, twenty-four.

2. The Oregon Mission. -- This mission was commenced by Rev. Messrs. Jason and Daniel Lee, and now numbers twenty-one missionaries, including preachers, teachers, physicians, farmers, mechanics, &c. The greater part of these were sent out in 1840, making, with their wives and children, about fifty souls -- the largest missionary expedition going, at one time, from this country. They are now laying the foundations of their future work.

3. The Texas Mission was commenced by Rev. Dr. Ruter, assisted by two young preachers, who accompanied him to that country in 1837. An annual conference was established in this mission field in 1840, which now includes three regular presiding elders' districts, and eighteen stations and circuits. It numbers twenty-three travelling preachers, thirty-six local preachers, (i. e., lay preachers, who support themselves, and preach as they have opportunity) and two thousand seven hundred and ninety-five members. There is a college at Rutersville.

II. DOMESTIC MISSIONS.

1. German Missions. -- The first German mission was established in Cincinnati, in 1835, by Rev. William Nast. There are now seventeen German missions, containing about one thousand members, in the states of Ohio, Pennsylvania, Kentucky, Indiana, Illinois, Missouri, and New York. A German paper is published at Cincinnati, called The Christian Apologist, having eleven hundred subscribers.

2. Indian Missions. -- There are eighteen missions, and one manual labor school, among the Indians located within the bounds of Rock River, Michigan, Holston, Missouri, Mississippi, and Arkansas conferences. These now include two thousand six hundred and seventeen native church members.

3. Missions among the Slaves. -- There are forty-seven of these missions in successful operation, including twelve thousand three hundred and ninety-three in church fellowship.

4. Missions in Destitute Portions of the Country. -- There are one hundred and eight domestic missions of this kind, which embrace twenty-three thousand nine hundred and fifty-eight church members.

Aggregate.

Foreign missions -- sixty-three missionaries, four thousand three hundred and seventeen church members. -- Domestic missions -- one hundred and seventy-eight missionaries, forty-one thousand church members. -- Total -- two hundred and forty-one missionaries, forty-five thousand three hundred and seventeen church members.

The whole amount of missionary money collected for the year ending April 20, 1842, is one hundred and five thousand two hundred and eighty-one dollars; expended, one hundred and forty-nine thousand and sixty-five dollars.