First minister of Salem, Massachusetts, after receiving his education at Emanuel College, in Cambridge, became the minister of a church at Leicester, in England. While his popular talents filled his church with attentive hearers, such was the divine blessing upon his labors, that a deep attention to religious subjects was excited among his people. Becoming at length a conscientious Nonconformist to the rites of the English church, some of which he thought not only were unsupported by Scripture, but corrupted the purity of Christian worship and discipline, he was excluded from the parish church, and became obnoxious to the High Commission Court. One day two messengers came to his house, and with loud knocks cried out, "Where is Mr. Higginson? We must speak with Mr. Higginson!" His wife ran to his chamber, and entreated him to conceal himself; but he replied, that he should acquiesce in the will of God. He went down, and, as the messengers entered the hall, they presented him with some papers, saying, in a rough manner, "Sir, we came from London, and our business is to convey you to London, as you may see by those papers." "I thought so," exclaimed Mrs. Higginson, weeping; but a woman's tears could have but little effect upon hard-hearted pursuivants. Mr. Higginson opened the packet to read the form of his arrest, but, instead of an order from Bishop Laud for his seizure, he found a copy of the charter of Massachusetts, and letters from the governor and company, inviting him to embark with them for New England. The sudden transition of feeling from despondence to joy, may be better imagined than described.

Having sought advice and implored the divine direction, he resolved to accept the invitation. In his farewell sermon, preached before a vast assembly, he declared his persuasion, that England would be chastised by war, and that Leicester would have more than an ordinary share of sufferings. It was not long before his prediction was verified. It is not meant that he claimed the power of foretelling future events, but he could reason with considerable accuracy from cause to effect, knowing that iniquity is generally followed by its punishment; and he lived in an age when it was usual for ministers to speak with more confidence, and authority, and efficacy, than at present. He sailed from Gravesend, April 25, 1629, accompanied by Mr. Skelton, whose principles accorded with his own. When he came to the Land's End, he called his children and the other passengers on deck to take the last view of their native country; and he now exclaimed, "Farewell, England! farewell, the church of God in England, and all the Christian friends there! We do not go to America as separatists from the church of England, though we cannot but separate from its corruptions." He then concluded with a fervent prayer for the king, church, and state, in England. He arrived at Cape Ann, June 27, 1629, and, having spent the next day there, which was Sunday, on the 29th he entered the harbor of Salem. July the 20th was observed as a day of fasting by the appointment of Governor Endicott, and the church then made choice of Mr. Higginson to be their teacher, and Mr. Skelton their pastor.

Thus auspicious was the commencement of the settlement of Naumkeag, or Salem; but the scene was soon changed. During the first winter, about one hundred persons died, and Mr. Higginson was soon seized with a hectic, which terminated his days in August, 1630, aged forty-two. In his last sickness, he was reminded of his benevolent exertions in the service of the Lord Jesus Christ. To consoling suggestions of this kind he replied, "I have been an unprofitable servant, and all my desire is to win Christ, and be found in him, not having my own righteousness."