"And I heard another voice from heaven, saying, Come out of her, my people, that ye partake not of her sins, and that ye receive not of her plagues, for her sins have reached to heaven, and God hath remembered her iniquities! Reward her even as she rendered to you, and double to her according to her works, in the cup which she hath poured out, pour out double to her. By as much as she hath glorified herself, and lived luxuriously, so much torment and mourning give her; for she saith in her heart, I sit a queen, and am not a widow, and shall see no mourning. On this account, her plagues will come in one day, death, and mourning, and famine; and she will be burned up with fire; for strong is the Lord God, who judgeth her." -- Rev.18:4-8.

So long as the true character of the apostate church was unperceived, she would contain many good, as well as a multitude of bad members. The voice from heaven, indicates an epoch when there should be a widely extended and marked separation between these two classes. Till the time of that separation should be indicated, the children of God would be justified in continuing members of her communion; but not subsequently. The condition of Babylon, at the time of her fall, indicates that the separation must take place in near connection with that event; and the cry must synchronize with that of the third angel in Rev.14:9, -- which symbolized a body of men who should insist on such a separation from the Papacy as that here symbolized.

After the discovery that the church of Rome was the Babylon of the Apocalypse, the reformers began to call on the people of God to desert her communion; and the formation of the reformed churches was the consequence. This was preached wherever the Reformation extended, and has been continued to the present time. The Protestant churches have proclaimed connection with Romanism, an obstacle to salvation; and have called on its Christian members to come out from her abominations. Even the name "Protestant," was given because of their protestation against the corruptions of the Papal See.

After the fall of ancient Babylon, and before her destruction, the people were, in like manner, commanded to forsake her. Said Jeremiah: "Flee out of the midst of Babylon, and deliver every man his soul: be not cut off in her iniquity; for this is the time of the Lord's vengeance; he will render unto her a recompense. Babylon is suddenly fallen and destroyed: howl for her; take balm for her pain, if so be she may be healed. We would have healed Babylon, but she is not healed: forsake her, and let us go every one into his own country: for her judgment reacheth unto heaven, and is lifted up even to the skies," Jer.51:6, 8, 9. And Isaiah said: "Go ye forth of Babylon, flee ye from the Chaldeans, with a voice of singing declare ye, tell this, utter it even to the end of the earth; say ye, The Lord hath redeemed his servant Jacob," Isa.48:20. "Depart ye, depart ye, go ye out from thence, touch no unclean thing; go ye out of the midst of her; be ye clean, that bear the vessels of the Lord," Isa.52:11.

Sins reaching to heaven, indicate great wickedness. Thus God said to Jonah: "Go to Nineveh, that great city, and cry against it; for their wickedness is come up before me," Jonah 1:2. And he said of old Babylon: "Her judgment reacheth unto heaven, and is lifted up even to the skies," Jer.51:9.